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pitt b, zannad f, remme wj, et al; for the randomized aldactone evaluation study investigators.
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aldactone counteracts secondary aldosteronism induced by the volume depletion and associated sodium loss caused by active diuretic therapy.
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before taking this medication, talk to your doctor if you are taking any of the following drugs a nonsteroidal anti-inflammatory drug nsaid such as ibuprofen motrin, advil, others , ketoprofen orudis, orudis kt, oruvail , naproxen naprosyn, aleve, anaprox ; diclofenac voltaren, cataflam , etodolac lodine , fenoprofen nalfon , flurbiprofen ansaid , indomethacin indocin , nabumetone relafen , oxaprozin daypro , piroxicam feldene , sulindac clinoril , or tolmetin tolectin celecoxib celebrex , rofecoxib vioxx , or valdecoxib bextra aspirin or another salicylate form of aspirin such as salsalate disalcid , choline salicylate, or magnesium salicylate a diuretic water pill such as hydrochlorothiazide hctz, hydrodiuril, others , chlorothiazide diuril, others , chlorthalidone thalitone, hygroton , bumetanide bumex , ethacrynic acid edecrin , furosemide lasix , spironolactone aldactone , or amiloride midamor an angiotensin-converting-enzyme inhibitor ace inhibitor such as benazepril lotensin , captopril capoten , enalapril vasotec , fosinopril monopril , lisinopril prinivil, zestril , moexipril univasc , quinapril accupril , ramipril altace , and others an anticoagulant such as warfarin coumadin a seizure medicine such as carbamazepine tegretol or phenytoin dilantin, phenytek methotrexate rheumatrex, trexall lithium eskalith, lithobid, others cyclosporine sandimmune, neoral you may not be able to take this medication, or you may require a speical dosage or monitoring during treatment if you are taking any of the medicines listed above.
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be sure to mention the following angiotensin-converting enzyme ace inhibitors such as benazepril lotensin, in lotrel , captopril capoten, in capozide , enalapril vasotec , fosinopril, lisinopril in prinzide, in zestoretic , moexipril univasc, in uniretic , perindopril, aceon , quinapril accupril, in accuretic, in quinaretic , ramipril altace , and trandolapril mavik, in tarka ; aspirin and other nonsteroidal anti-inflammatory medications nsaids such as ibuprofen advil, motrin and naproxen aleve, naprosyn and selective cox-2 inhibitors such as celecoxib celebrex ; cyclosporine gengraf, neoral, sandimmune ; diuretics water pills , including potassium-sparing diuretics such as amiloride midamor , spironolactone aldactone, in aldactazide , and triamterene dyrenium, in dyazide, in maxzide ; gemfibrozil lopid , other medications to treat high blood pressure or a heart problem; potassium supplements; rifampin rifadin, rimactane, in rifamate, in rifater ; and ritonavir norvir .
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for the treatment of hypokalemia, daily recommended dosage of aldactone is between 25mg and 100mg whereas patients suffering from severe heart failure, 25mg of aldactone should be administered daily.
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