Posted on 24.08.2018 in the General category
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The risk of suicidal thoughts or behavior was generally consistent among drugs in the data analyzedThe finding of increased risk with AEDs of varying mechanism of action and across a range of indications suggests that the risk applies to all AEDs used for any indicationThe risk did not vary substantially by age5 to 100 yearsin the clinical trials analyzed.
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It is recommended that LAMICTAL not be restarted in patients who discontinued due to rash associated with prior treatment with lamotrigine unless the potential benefits clearly outweigh the risksIf the decision is made to restart a patient who has discontinued LAMICTALthe need to restart with the initial dosing recommendations should be assessedThe greater the interval of time since the previous dosethe greater consideration should be given to restarting with the initial dosing recommendationsIf a patient has discontinued lamotrigine for a period of more than 5 half-livesit is recommended that initial dosing recommendations and guidelines be followedThe half-life of lamotrigine is affected by other concomitant medicationssee CLINICAL PHARMACOLOGY
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lamictal is quickly absorbed into the systemic blood flow after the oral use.
