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Studies to evaluate possible interactions between REVIA and drugs other than opiates have not been performedConsequentlycaution is advised if the concomitant administration of REVIA and other drugs is required.
In view of the lack of actual experience in the treatment of REVIA overdosepatients should be treated symptomatically in a closely supervised environmentPhysicians should contact a poison control center for the most up-to-date information.
Allodynic TherapeuticsLLC1785 NE 123rd StreetNorth MiamiFL 33181-2537.
To prevent occurrence of precipitated withdrawal in patients dependent on opioidsor exacerbation of a pre-existing subclinical withdrawal syndromeopioid-dependent patientsincluding those being treated for alcohol dependenceshould be opioid-freeincluding tramadolbefore starting REVIA treatmentAn opioid-free interval of a minimum of 7 to 10 days is recommended for patients previously dependent on short-acting opioidsPatients transitioning from buprenorphine or methadone may be vulnerable to precipitation of withdrawal symptoms for as long as two weeks.
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