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Posted on 24.08.2018 in the General category

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A syndrome consisting of potentially irreversibleinvoluntarydyskinetic movements may develop in patients treated with antipsychotic drugssee ADVERSE REACTIONSAlthough the prevalence of the syndrome appears to be highest among the elderlyespecially elderly womenit is impossible to rely upon prevalence estimates to predictat the inception of antipsychotic treatmentwhich patients are likely to develop the syndromeWhether antipsychotic drug products differ in their potential to cause tardive dyskinesia is unknown.

284 patients who participated in 3 double-blindplacebo-controlled clinical trials with haloperidoloral formulation2 to 20 mg/daytwo trials were in the treatment of schizophrenia and one in the treatment of bipolar disorder1295 patients who participated in 16 double-blindactive comparator-controlled clinical trials with haloperidolinjection or oral formulation1 to 45 mg/dayin the treatment of schizophrenia.

FDA pregnancy category CTell your doctor if you are pregnant or plan to become pregnant while using this medication.

The recommended oral dose for schizophrenia is 0.5-5 mg two or three times daily up to a maximum dose of 30 mg dailyThe lactate solution dose is 2-5 mg every 4-8 hours as needed by intramuscular injectionThe lactate solution may also be administered by intravenous injection at 1-2 mg every 2-4 hours and titrated to effectThe maximum single injection dose is 50 mg and the maximum daily dose is 500 mg dailyThe dose for the decanoate solution is 10-20 times the daily oral dose once monthly by intramuscular injectionThe decanoate solution should not be administered intravenouslyThe recommended dose for treating Tourette’s syndrome is 0.5-5 mg orally two or three times daily.

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