Posted on 24.08.2018 in the General category
Lorraine traer-clark collapsed in january 1995 after taking lariam for six months while working in tanzania for an international mining company.
Get emergency medical help if you have any of these signs of an allergic reactionhivesdifficulty breathingswelling of your facelipstongueor throat.
In healthy adultsthe apparent volume of distribution is approximately 20 L/kgindicating extensive tissue distributionMefloquine may accumulate in parasitized erythrocytesExperiments conducted in vitro with human blood using concentrations between 50 and 1000 mg/mL showed a relatively constant erythrocyte-to-plasma concentration ratio of about 2 to 1The equilibrium reached in less than 30 minutes was found to be reversibleProtein binding is about 98
In pediatric patientsthe administration of Lariam for the treatment of malaria has been associated with early vomitingIn some casesearly vomiting has been cited as a possible cause of treatment failuresee PRECAUTIONSIf a significant loss of drug product is observed or suspected because of vomitinga second full dose of Lariam should be administered to patients who vomit less than 30 minutes after receiving the drugIf vomiting occurs 30 to 60 minutes after a dosean additional half-dose should be givenIf vomiting recursthe patient should be monitored closely and alternative malaria treatment considered if improvement is not observed within a reasonable period of time.
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lariam belongs to a group of medicines called quinolones pronounced kwin- o-lones .
