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Breast cancer is rare among women under 40 years of age whether or not they take COCsWhilst this background risk increases with agethe excess number of breast cancer diagnoses in current and recent COC users is small in relation to the overall risk of breast cancer.
After pregnancyGINETTE 35 can be started 21 days after a vaginal deliveryprovided that the patient is fully ambulant and there are no puerperal complicationsAdditional contraceptive precautions will be required for the first 7 days of tablet takingSince the first postpartum ovulation may precede the first bleedinganother method of contraception should be used in the interval between childbirth and the first course of tabletsLactation is contraindicated with GINETTE 35After a first trimester abortionGINETTE 35 may be started immediatelyin which case no additional contraceptive precautions are required.
Insulin-dependent diabetics without vascular disease can use CPA+EEHoweverit should be remembered that all diabetics are at an increased risk of arterial disease and this should be considered when prescribing COCs or CPA+EEDiabetics with existing vascular disease are contraindicated from using CPA+EE.
The absolute bioavailability of CPA is almost complete88of doseThe relative bioavailability of CPA from CPA+EE was 109when compared to an aqueous microcrystalline suspension.
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