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Patients with decreased renal function require lower doses of Zyloprim than those with normal renal functionLower than recommended doses should be used to initiate therapy in any patients with decreased renal function and they should be observed closely during the early stages of administration of ZyloprimIn patients with severely impaired renal function or decreased urate clearancethe half-life of oxipurinol in the plasma is greatly prolongedThereforea dose of 100 mg per day or 300 mg twice a weekor perhaps lessmay be sufficient to maintain adequate xanthine oxidase inhibition to reduce serum urate levels.
Since other medications may interact with allopurinoltell your doctor about all prescriptionnon-prescriptionillegalrecreationalherbalnutritionalor dietary drugs you are takingespeciallyAzathioprineImuranChlorpropamideDiabineseCyclosporineGengrafSandimmuneNeoralMercaptopurinePurinetholAntibiotics such as ampicillinPrincipenOmnipenothersor amoxicillinAmoxilAugmentinTrimoxWymoxBlood thinners such as warfarinCoumadinDiureticswater pills)
The medication may also be used to treat seizuresinfectionsand pain caused by pancreas diseaseIt is sometimes used to improve survival after bypass surgeryprevent rejection of kidney transplantsor reduce ulcer relapses.
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allopurinol zyloprim, aloprim is a xanthine oxidase inhibitor that prevents attacks of gout and renal stones in affected patients, and also treats some complications of cancer chemotherapy.
