Posted on 24.08.2018 in the General category
Get emergency medical help if you have signs of an allergic reaction to tegretol hives, difficulty breathing, swelling of your face, lips, tongue, or throat.
When carbamazepine is added to aripiprazolethe aripiprazole dose should be doubledAdditional dose increases should be based on clinical evaluationIf carbamazepine is later withdrawnthe aripiprazole dose should be reducedWhen carbamazepine is used with tacrolimusmonitoring of tacrolimus blood concentrations and appropriate dosage adjustments are recommendedThe use of concomitant strong CYP3A4 inducers such as carbamazepine should be avoided with temsirolimusIf patients must be coadministered carbamazepine with temsirolimusan adjustment of temsirolimus dosage should be consideredThe use of carbamazepine with lapatinib should generally be avoidedIf carbamazepine is started in a patient already taking lapatinibthe dose of lapatinib should be gradually titrated upIf carbamazepine is discontinuedthe lapatinib dose should be reducedConcomitant use of carbamazepine with nefazodone results in plasma concentrations of nefazodone and its active metabolite insufficient to achieve a therapeutic effectCoadministration of carbamazepine with nefazodone is contraindicatedsee CONTRAINDICATIONSMonitor concentrations of valproate when Tegretol is introduced or withdrawn in patients using valproic acid.
The relative risk for suicidal thoughts or behavior was higher in clinical trials for epilepsy than in clinical trials for psychiatric or other conditionsbut the absolute risk differences were similar for the epilepsy and psychiatric indications.
Lowest known lethal doseadults3.2 ga 24-year-old woman died of a cardiac arrest and a 24-year-old man died of pneumonia and hypoxic encephalopathychildren4 ga 14-year-old girl died of a cardiac arrest1.6 ga 3-year-old girl died of aspiration pneumonia
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