Posted on 12.09.2018 in the General category
Fda approval for the new indication was partially based on a randomized study of more than 6000 patients in which a 12-dose, once-weekly regimen of directly observed therapy dot with rifapentine plus isoniazid was compared with a regimen consisting of 9 months of self-administered daily isoniazid.
This medication may be prescribed for other usesask your doctor or pharmacist for more information.
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In South Africa isoniazid is registered for the treatment of tuberculosis and mycobacterium infections other than tuberculosis.
The risk of peripheral neuropathy is excluded if vulnerable patients receive daily supplements of pyridoxineOther less common forms of neurological disturbanceincluding optic neuritistoxic psychosis and generalized convulsionscan develop in susceptible individualsparticularly in the later stages of treatmentand occasionally necessitate the withdrawal of isoniazid.
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ulipristal minor ulipristal is a substrate of cyp3a4 and isoniazid, inh is a cyp3a4 inhibitor.
