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The influence of terbinafine on the pharmacokinetics of fluconazolecotrimoxazoletrimethoprim and sulfamethoxazolezidovudine or theophylline was not considered to be clinically significant.
Take the missed dose as soon as you rememberSkip the missed dose if it is almost time for your next scheduled doseDo not take extra medicine to make up the missed dose.
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Terbinafinean allylamine antifungalinhibits biosynthesis of ergosterolan essential component of fungal cell membranevia inhibition of squalene epoxidase enzymeThis results in fungal cell death primarily due to the increased membrane permeability mediated by the accumulation of high concentrations of squalene but not due to ergosterol deficiencyDepending on the concentration of the drug and the fungal species test in vitroterbinafine hydrochloride may be fungicidalHoweverthe clinical significance of in vitro data is unknown.
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