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There is no evidence from randomised controlled trials of protection against myocardial infarction in women with or without existing CAD who received combined estrogen-progestogen or estrogen-only HRTRandomised controlled data found no increased risk of CAD in hysterectomised women using estrogen-only therapy.
The effect of hepatic impairment on the pharmacokinetics of PREMARIN Vaginal Cream has not been studied.
Many drugs can interact with conjugated estrogensThis includes prescription and over-the-counter medicinesvitaminsand herbal productsNot all possible interactions are listed in this medication guideTell your doctor about all your current medicines and any medicine you start or stop using.
A history of hormone-related canceror cancer of the breastuterus/cervixor vagina.
Premarin is used to treat menopause symptoms such as hot flashes and vaginal changesand to prevent osteoporosisbone lossin menopausal women.
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