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Carbidopa allows patients treated for Parkinson’s disease to use much lower doses of levodopaSome patients who responded poorly to levodopa have improved on SINEMETThis is most likely due to decreased peripheral decarboxylation of levodopa caused by administration of carbidopa rather than by a primary effect of carbidopa on the nervous systemCarbidopa has not been shown to enhance the intrinsic efficacy of levodopa.
Levodopa has been detected in human milkCaution should be exercised when SINEMET is administered to a nursing woman.
These are possible side effects of SINEMETFor the most part these have been mild.
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if the patient anticipates disconnecting the pump for a short period of time less than 2 hours such as to swim, shower, or short medical procedure , no supplemental oral medication is needed, but the patient may be advised to take an extra-dose of sinemet sr before disconnecting.
