Posted on 11.05.2018 in the General category
Some conditions increase your chance of getting lactic acidosis, or cause other problems if you take metformin.
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this trial enrolled patients n 338 who were newly diagnosed with diabetes, patients treated only with diet and exercise, patients treated with a single anti-diabetic medication sulfonylureas, alpha-glucosidase inhibitors, thiazolidinediones, or meglitinides , and patients n 368 receiving metformin up to 1500 mg day plus a sulfonylurea at a dose equal to or less than one-half the maximum dose.
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view articlepubmedgoogle scholar correia s, carvalho c, santos ms, seica r, oliveira cr, moreira pi mechanisms of action of metformin in type 2 diabetes and associated complications an overview.
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warning for kazano alogliptin and metformin hcl risk of lactic acidosis.
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further tests reveal metformin as a versatile drug and by so effectively treating diabetes, associated conditions are likely to be reduced.
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glucovance should be given with meals and should be initiated at a low dose, with gradual dose escalation as described below, in order to avoid hypoglycemia largely due to glyburide , reduce gi side effects largely due to metformin , and permit determination of the minimum effective dose for adequate control of blood glucose for the individual patient.
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