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drugs that may decrease phenytoin levels and reduce effectiveness include carbamazepine, chronic alcohol abuse, reserpine, and sucralfate carafate .
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other useful agents of the present invention may include digestive agents, such as sulfasalazine commercially available as azulfidine , rabeprazole sodium commercially available as aciphex , lubiprostone commercially available as amitiza , dicyclomine hydrochloride commercially available as bentyl , sucralfate commercially available as carafate , lactulose commercially available as chronulac , docusate commercially available as colace , balsalazide disodium commercially available as colazal , losartan potassium commercially available as cozaar , olsalazine sodium commercially available as dipentum , chlordiazepoxide hydrochloride, clidinium bromide commercially available as librax , esomeprazole magnesium commercially available as nexium , famotidine commercially available as pepcid , lansoprazole commercially available as prevacid , lansoprazole and naproxen commercially available as prevacid naprapac ,.
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in vitro in human subjects, carafate given in doses recommended for ulcer therapy inhibits pepsin activity in gastric juice by 32 .
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