Posted on 13.05.2018 in the General category
The influence of efavirenz on the pharmacokinetics of a twice-daily combination of indinavir and low-dose ritonavir in healthy volunteers.
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progesterone moderate indinavir decreases the metabolism of oral contraceptives and non-oral combination contraceptives; the auc for ethinyl estradiol and norethindrone increased by 24 -17 and 26 -14 , respectively, when coadministered with indinavir.
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ibrutinib major avoid the concomitant use of ibrutinib and indinavir; ibrutinib plasma concentrations may increase resulting in severe ibrutinib toxicity e.
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