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antacids moderate to limit any interaction, administer isoniazid, inh 1 or 2 hours before any antacids.
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malabsorption of isoniazid and other antituberculous drugs may occur in patients with hiv infection and tuberculosis, and may contribute to acquired drug resistance and reduced efficacy of tuberculosis treatment.
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isavuconazole, the active moiety of isavuconazonium, is a sensitive substrate of the hepatic isoenzyme cyp3a4; isoniazid is an inhibitor of this enzyme.
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