Posted on 13.05.2018 in the General category
Fluoxetine, a potent inhibitor of cyp2d6, may lead to reduced concentrations of endoxifen, one of the most important active metabolites of tamoxifen.
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in healthy subjects, 20 mg of metoclopramide and 60 mg of fluoxetine a strong cyp2d6 inhibitor were administered, following prior exposure to 60 mg fluoxetine orally for 8 days.
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anticoagulants eg, warfarin , aspirin, corticosteroids eg, prednisone , heparin, or selective serotonin reuptake inhibitors ssris eg, fluoxetine because the risk of stomach bleeding may be increased probenecid because it may increase the risk of feldene s side effects cyclosporine, hydantoins eg, phenytoin , lithium, methotrexate, quinolones eg, ciprofloxacin , sulfonamides eg, sulfamethoxazole , or sulfonylureas eg, glipizide because the risk of their side effects may be increased by feldene angiotensin-converting enzyme ace inhibitors eg, enalapril or diuretics eg, furosemide, hydrochlorothiazide because their effectiveness may be decreased by feldene.
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