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Gabapentin does not exhibit affinity for benzodiazepineopiatemudelta or kappaor cannabinoid 1 receptor sitesA small number of postmarketing cases report gabapentin misuse and abuseThese individuals were taking higher than recommended doses of gabapentin for unapproved usesMost of the individuals described in these reports had a history of poly-substance abuse or used gabapentin to relieve symptoms of withdrawal from other substancesWhen prescribing gabapentin carefully evaluate patients for a history of drug abuse and observe them for signs and symptoms of gabapentin misuse or abusee.gdevelopment of toleranceself-dose escalationand drug-seeking behavior

All pharmacological actions following gabapentin administration are due to the activity of the parent compoundgabapentin is not appreciably metabolized in humans.

Take the missed dose as soon as you rememberBe sure to take the medicine with foodSkip the missed dose if it is almost time for your next scheduled doseDo not take extra medicine to make up the missed dose.

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