Posted on 24.08.2018 in the General category
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Keep this medication in the carton or container it came intightly closedand out of reach of childrenStore promethazine tablets and liquid at room temperature and away from excess heat and moisturenot in the bathroomStore promethazine suppositories in the refrigeratorProtect the medication from light.
Use of promethazine hydrochloride tablets in patients with compromised respiratory functione.gCOPDsleep apneashould be avoided.
Treatment of overdosage is essentially symptomatic and supportiveOnly in cases of extreme overdosage or individual sensitivity do vital signsincluding respirationpulseblood pressuretemperatureand EKGneed to be monitoredActivated charcoal orally or by lavage may be givenor sodium or magnesium sulfate orally as a catharticAttention should be given to the reestablishment of adequate respiratory exchange through provision of a patent airway and institution of assisted or controlled ventilationDiazepam may be used to control convulsionsAcidosis and electrolyte losses should be correctedNote that any depressant effects of promethazine HClpromethazine hydrochlorideare not reversed by naloxoneAvoid analeptics which may cause convulsionsThe treatment of choice for resulting hypotension is administration of intravenous fluidsaccompanied by repositioning if indicatedIn the event that vasopressors are considered for the management of severe hypotension which does not respond to intravenous fluids and repositioningthe administration of norepinephrine or phenylephrine should be consideredEPINEPHRINE SHOULD NOT BE USEDsince its use in patients with partial adrenergic blockade may further lower the blood pressureExtrapyramidal reactions may be treated with anticholinergic antiparkinsonian agentsdiphenhydramineor barbituratesOxygen may also be administered.
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