Posted on 24.08.2018 in the General category
Immediate art compared to starting treatment according to who guidelines between 2008 and 2012, isoniazid for the prevention of tuberculosis compared to placebo.
3Product InformationINHisoniazidCiba PharmaceuticalsSummitNJ.
Recommended for patients aged 12 years and older who are at high risk for developing TB disease including anyone who has had recent exposure to contagious TBconversion from negative to positive on a test for TB infectionor a chest X-ray indicating prior TB disease Persons with HIV who are otherwise healthy and not taking antiretrovirals may also use this regimen 900 mg PO once weekly x3 monthsadminister with rifapentine 900 mg once weeklyAdministered as DOT Not recommended for children 35 years old weigh use against risk of hepatitis.
Nauseavomitingdizzinessblurred vision and slurring of speech occur within 30 minutes to 3 hours of overdosageMassive poisoning results in coma preceded by respiratory depression and stuporSevere intractable seizures may occurEmesis and gastric lavage can be of value if instituted within a few hours of ingestionSubsequentlyhaemodialysis may be of valueAdministration of high doses of pyridoxine is necessary to prevent peripheral neuritis.
PregnancyavoidIt is unknown how this medication may affect your babyConsult your doctor before using this drugor if you are planning to fall pregnantBreastfeedingavoidIt is unknown how this medication may affect your babyConsult your doctor before usePorphyriaavoidThis medication may cause serious adverse effectsConsult your doctor before useInfants and childrenthis medication is safe for use in children at the recommended doseThe elderlycaution is advised in the elderly as the risk of adverse effects is increasedDriving and hazardous workno special precautions need to be takenAlcoholavoid concomitant use of alcohol with this medication.
Keep all appointments with your doctor and the laboratoryYour doctor will order certain lab tests to check your response to isoniazid.
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