Posted on 13.05.2018 in the General category
In 1994, naltrexone was approved by the fda to treat alcohol dependence after the medication was shown to reduce the frequency of drinking and likelihood of relapse to heavy drinking garbutt et al.
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they stated that it is likely that a subgroup of children with autism and abnormal endorphin levels may respond to naltrexone and identifying the characteristics of these children must become a priority.
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your healthcare provider may order tests to determine if you ve taken any opioid medicines or used any opioid street drugs in the past seven to 10 days before recommending naltrexone.
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oral naltrexone is not a highly recommended therapy for the following reasons it has a very low retention rate concern about its safety in the setting of liver disease it blocks the analgesic effects of opioid agonists and should be discontinued 72 hours prior to elective surgery there is an elevated risk of fatal overdose upon discontinuation of oral naltrexone therapy 24 .
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high doses of naltrexone hydrochloride generally 1,000 mg kg produced salivation, depression reduced activity, tremors, and convulsions.
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