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In a 26-wk, placbo-contolld, dos-anging monothapy study, man sum tiglycids dcasd in th 15-mg, 30-mg, and 45-mg pioglitazon dos goups compad ta man incas in th placbgoup. Man HDL cholstol incasd ta gat xtnt in patints tatd with pioglitazon than in th placbo-tatd patints. Th w nconsistnt dincs LDL and total cholstol in patints tatd with pioglitazon compad tplacb(s Tabl 16).

Mtomin may stimulat ovulation in a pmnopausal woman and may incas th isk unintndd pgnancy. Talk tyou doctabout you isk.

15 mg/500 mg twic daily 15 mg/850 mg onc daily and gadually titatd, as ndd, at assssing adquacy thaputic spons and tolability, patints with Nw Yok Hat Association (NYHA) Class I Class II congstiv hat ailu: 15 mg/500 mg 15 mg/850 mg onc daily and gadually titatd, as ndd, at assssing adquacy thaputic spons and tolability, patints inadquatly contolld on mtomin monothapy: 15 mg/500 mg twic daily 15 mg/850 mg onc twic daily (dpnding on th dos mtomin alady bing takn) and gadually titatd, as ndd, at assssing adquacy thaputic spons and tolability, patints inadquatly contolld on pioglitazon monothapy: 15 mg/500 mg twic daily 15 mg/850 mg onc daily and gadually titatd, as ndd, at assssing adquacy thaputic spons and tolability, patints wha changing om combination thapy pioglitazon plus mtomin as spaat tablts: ACTOPLUS MT should b takn at doss that a as clos as possibl tth dos pioglitazon and mtomin alady bing takn.

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