Posted on 24.08.2018 in the General category
Cyclosporine neoral, sandimmune, gengraf , tacrolimus prograf , lithium eskalith, lithobid , digoxin lanoxin , steroids prednisone and others , a blood thinner such as warfarin coumadin, jantoven , insulin or oral diabetes medication, other blood pressure medications, an ace inhibitor such as benazepril lotensin , enalapril vasotec , lisinopril prinivil, zestril , quinapril accupril , ramipril altace , and others, candesartan atacand , eprosartan teveten , irbesartan avapro , losartan cozaar , olmesartan benicar , telmisartan micardis , or valsartan diovan , or indomethacin or other nsaids non-steroidal anti-inflammatory drugs such as aspirin, ibuprofen advil, motrin , naproxen aleve, naprosyn, naprelan, treximet , celecoxib celebrex , diclofenac arthrotec, cambia, cataflam, voltaren, flector patch, pennsaid, solareze , indomethacin indocin , meloxicam mobic , and others.
The recommended initial dose is 2.5 mg/dayIf requiredthe dose should be increased graduallydepending on the patient responseThe usual effective dosage range is 5 to 20 mg/day administered in a single daily doseDose titration may be performed over a 2 to 4 week periodor more rapidly if indicated by the presence of residual signs and symptoms of heart failure.
If hypotension occursthe patient should be placed in supine position andif necessaryreceive an i.vinfusion of normal salineA transient hypotensive response is not a contraindication to further doses which usually can be given without difficulty once the blood pressure has increased after volume expansion.
In acute myocardial infarctiontreatment with lisinopril should not be initiated in patients with evidence of renal dysfunctiondefined as serum creatinine concentration exceeding 177 mol/L and/or proteinuria exceeding 500 mg/24 hoursIf renal dysfunction develops during treatment with lisinoprilserum creatinine concentration exceeding 265 mol/L or a doubling from the pretreatment valuethen the physician should consider withdrawal of lisinopril.
Patients with Impaired Liver FunctionHepatitisjaundicehepatocellular and/or cholestaticelevations of liver enzymes and/or serum bilirubin have occurred during therapy with lisinopril in patients with or without pre-existing liver abnormalitiessee Adverse EffectsIn most cases the changes were reversed on discontinuation of the drug.
Dizzinesshypotensionheadachecoughchest painrenal dysfunctionhyperkalemiaangioedemarareliver dysfunctionblood dyscrasias.
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