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Rifampin may increase the metabolismdestructionof bisoprololpossibly making bisoprolol less effectiveCertain calcium channel blockersCCBsespecially verapamilCalanIsoptinand diltiazemCardizemTiazacmay enhance the effect of bisoprolol on the heartIn some patientsthis may cause excessive slowing of the heart rate or reduce the heart’s ability to beatThe use of digoxinLanoxinwith bisoprolol also may cause an excessive reduction in heart rate.
Heart failurecongestiveis caused by many conditions including coronary artery diseaseheart attackcardiomyopathyand conditions that overwork the heartSymptoms of heart failure include.
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