Posted on 24.08.2018 in the General category
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Estrogens with or without progestins should be prescribed at the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman.
Undiagnosed abnormal genital bleeding Knownsuspectedor history of breast cancer Known or suspected estrogen-dependent neoplasia Active DVTPEor a history of these conditions Active arterial thromboembolic diseasefor examplestroke and MIor a history of these conditions Known anaphylactic reaction or angioedema to PREMARIN Vaginal Cream Known liver dys function or disease Known protein Cprotein S or antithrombin deficiency or other known thrombophilic disorders Known or suspected pregnancy.
The WHI Memory StudyWHIMSestrogen-alone ancillary study of WHI reported an increased risk of developing probable dementia in postmenopausal women 65 years of age or older during 5.2 years of treatment with daily CE0.625 mgalonerelative to placeboIt is unknown whether this finding applies to younger postmenopausal womensee WARNINGS AND PRECAUTIONSUse In Specific Populationsand Clinical Studies
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