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Maintenanceduring remission15 mg/m2 IM or orally twice a weekAlternate remission dosing2.5 mg/kg IV every 14 days.
Increased side effects from methotrexateTaking methotrexate with certain medications raises your risk of side effects from methotrexateThis is because the amount of methotrexate in your body may be increasedExamples of these drugs include:
Rememberkeep this and all other medicines out of the reach of childrennever share your medicines with othersand use methotrexate only for the indication prescribed.
If you have kidney problems or excess body waterascitespleural effusionyou must be closely monitored and your dose may be adjusted or stopped by your doctor.
Methotrexate can harm an unborn baby or cause birth defectswhether the mother or father is taking this medicine.
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here is an informational page from the national institute of health methotrexate info page.