Posted on 25.08.2018 in the General category
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Table 5 lists adverse reactions in a controlled clinical study of monotherapy in adults not previously treated with other AEDs that occurred in at least 2of adult patients with epilepsy treated with TRILEPTAL or placebo and were numerically more common in the patients treated with TRILEPTAL.
Oxcarbazepine is cleared from the body mostly in the form of metabolites which are predominantly excreted by the kidneysMore than 95of the dose appears in the urinewith less than 1as unchanged oxcarbazepineFecal excretion accounts for less than 4of the administered doseApproximately 80of the dose is excreted in the urine either as glucuronides of MHD49or as unchanged MHD27the inactive DHD accounts for approximately 3and conjugates of MHD and oxcarbazepine account for 13of the dose.
Instruct patients that a fever associated with other organ system involvemente.grashlymphadenopathyhepatic dysfunctionmay be drug-related and should be reported to their healthcare provider immediatelysee WARNINGS AND PRECAUTIONS
Tell your healthcare provider about all the medicines you takeincluding prescription and over-the-counter medicinesvitaminsand herbal supplementsTaking TRILEPTAL with certain other medicines may cause side effects or affect how well they workDo not start or stop other medicines without talking to your healthcare provider.
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