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following oral administration, the percentage of ranitidine recovered unchanged in urine over 24 to 48 hours is about 30 of the dosage, with the main metabolite, the n-oxide, accounting for 1.
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h2 blockers contain cimetidine, ranitidine, famotidine and nizatidine and this act as by blocking histamine, which stimulates acid discharging.
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this led to substantial changes in some countries in terms of the relative costs of omeprazole and ranitidine.
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